Cytosolic phospholipase A(2 )alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice

BACKGROUND: The enzyme cytosolic phospholipase A(2 )alpha (cPLA(2)α) has been implicated in the progression of cerebral injury following ischemia and reperfusion. Previous studies in rodents suggest that cPLA(2)α enhances delayed injury extension and disruption of the blood brain barrier many hours...

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Detalles Bibliográficos
Autores principales: Kishimoto, Koji, Li, Rung-Chi, Zhang, Jian, Klaus, Judith A, Kibler, Kathleen K, Doré, Sylvain, Koehler, Raymond C, Sapirstein, Adam
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923122/
https://www.ncbi.nlm.nih.gov/pubmed/20673332
http://dx.doi.org/10.1186/1742-2094-7-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923122/
https://www.ncbi.nlm.nih.gov/pubmed/20673332
http://dx.doi.org/10.1186/1742-2094-7-42

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