Cargando…

Cytosolic phospholipase A(2 )alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice

BACKGROUND: The enzyme cytosolic phospholipase A(2 )alpha (cPLA(2)α) has been implicated in the progression of cerebral injury following ischemia and reperfusion. Previous studies in rodents suggest that cPLA(2)α enhances delayed injury extension and disruption of the blood brain barrier many hours...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kishimoto, Koji, Li, Rung-Chi, Zhang, Jian, Klaus, Judith A, Kibler, Kathleen K, Doré, Sylvain, Koehler, Raymond C, Sapirstein, Adam
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923122/ https://www.ncbi.nlm.nih.gov/pubmed/20673332 http://dx.doi.org/10.1186/1742-2094-7-42

Ejemplares similares

Astrocyte Inositol Triphosphate Receptor Type 2 and Cytosolic Phospholipase A(2) Alpha Regulate Arteriole Responses in Mouse Neocortical Brain Slices
por: He, Lihua, et al.
Publicado: (2012)

Cyclooxygenase-2 and Cytosolic Phospholipase A2 Are Overexpressed in Mucinous Pancreatic Cysts
por: Mensah, Elsie T., et al.
Publicado: (2019)

Impacts of Cytosolic Phospholipase A2, 15-Prostaglandin Dehydrogenase, and Cyclooxygenase-2 Expressions on Tumor Progression in Colorectal Cancer
por: Lim, Sung Chul, et al.
Publicado: (2010)

Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A(2)
por: Gijón, Miguel A., et al.
Publicado: (1999)

Regulatory role of cytosolic phospholipase A(2) alpha in the induction of CD40 in microglia
por: Malada-Edelstein, Yafa Fetfet, et al.
Publicado: (2017)

Bisgma Stimulates Prostaglandin E2 Production in Macrophages via Cyclooxygenase-2, Cytosolic Phospholipase A2, and Mitogen-Activated Protein Kinases Family
por: Kuan, Yu-Hsiang, et al.
Publicado: (2013)

Study of the Role of Cytosolic Phospholipase A(2) Alpha in Eicosanoid Generation and Thymocyte Maturation in the Thymus
por: Rousseau, Matthieu, et al.
Publicado: (2015)

The Step Further to Understand the Role of Cytosolic Phospholipase A(2) Alpha and Group X Secretory Phospholipase A(2) in Allergic Inflammation: Pilot Study
por: Pniewska, Ewa, et al.
Publicado: (2014)

Cytosolic Phospholipase A2 and Lysophospholipids in Tumor Angiogenesis
por: Linkous, Amanda G., et al.
Publicado: (2010)

Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells
por: Tunset, Hanna Maja, et al.
Publicado: (2019)

Cytosolic Phospholipase A(2) alpha/Arachidonic Acid Signaling Mediates Depolarization-Induced Suppression of Excitation in the Cerebellum
por: Wang, De-Juan, et al.
Publicado: (2012)

Cytosolic Phospholipase A2 Modulates TLR2 Signaling in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2015)

Dysregulation of phospholipase and cyclooxygenase expression is involved in Schizophrenia
por: Yang, Xuhan, et al.
Publicado: (2021)

Correction: Cytosolic Phospholipase A(2) alpha/Arachidonic Acid Signaling Mediates Depolarization-Induced Suppression of Excitation in the Cerebellum
por: Wang, De-Juan, et al.
Publicado: (2012)

Discrete Role for Cytosolic Phospholipase A(2)α in Platelets: Studies Using Single and Double Mutant Mice of Cytosolic and Group IIA Secretory Phospholipase A(2)
por: Wong, Dennis A., et al.
Publicado: (2002)

Inhibitory effects of thromboxane A(2) generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A(2) phosphorylation and arachidonic acid release
por: Shin, Jung-Hae, et al.
Publicado: (2019)

Prognostic significance of cytosolic phospholipase A2 expression in patients with colorectal cancer
por: Yoo, Young Sun, et al.
Publicado: (2011)

Cytosolic phospholipase A2 regulation in the hibernating thirteen-lined ground squirrel
por: Woods, Ashley K., et al.
Publicado: (2007)

Functions and mechanisms of cytosolic phospholipase A(2) in central nervous system trauma
por: Zhang, Hao-Jie, et al.
Publicado: (2022)

Expression of Cytosolic Phospholipase A2 (cPLA2)-Arachidonic Acid (AA)-Cyclooxygenase-2 (COX-2) Pathway Factors in Lung Cancer Patients and Its Implication in Lung Cancer Early Detection and Prognosis
por: Xin, Chunxia, et al.
Publicado: (2019)

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2019)

Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))
por: Psarra, Anastasia, et al.
Publicado: (2018)

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
por: Marusic, Suzana, et al.
Publicado: (2005)

Cytosolic Phospholipase A(2)α–deficient Mice Are Resistant to Collagen-induced Arthritis
por: Hegen, Martin, et al.
Publicado: (2003)

Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor
por: Noha, Stefan M., et al.
Publicado: (2012)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
por: Mahammad, Nur, et al.
Publicado: (2021)

Annexin I and dexamethasone effects on phospholipase and cyclooxygenase activity in human synoviocytes.
por: Sampey, A V, et al.
Publicado: (2000)

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2021)

Piperine Inhibits the Activities of Platelet Cytosolic Phospholipase A(2) and Thromboxane A(2) Synthase without Affecting Cyclooxygenase-1 Activity: Different Mechanisms of Action Are Involved in the Inhibition of Platelet Aggregation and Macrophage Inflammatory Response
por: Son, Dong Ju, et al.
Publicado: (2014)

Correction to “Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))”
por: Psarra, Anastasia, et al.
Publicado: (2019)

Unique targeting of cytosolic phospholipase A(2) to plasma membranes mediated by the NADPH oxidase in phagocytes
por: Shmelzer, Zeev, et al.
Publicado: (2003)

Pathways Regulating Cytosolic Phospholipase A(2) Activation and Eicosanoid Production in Macrophages by Candida albicans
por: Suram, Saritha, et al.
Publicado: (2010)

Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2013)

Predominant Role of Cytosolic Phospholipase A(2)α in Dioxin-induced Neonatal Hydronephrosis in Mice
por: Yoshioka, Wataru, et al.
Publicado: (2014)

Cytosolic Phospholipase A(2) Protein as a Novel Therapeutic Target for Spinal Cord Injury
por: Liu, Nai-Kui, et al.
Publicado: (2014)

Neuroprotective effert of carbon monoxide and Nrf2 in cerebral ischemia
por: Doré, Sylvain
Publicado: (2015)

2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A(2)
por: Kokotou, Maroula G., et al.
Publicado: (2017)

Aza-BODIPY probe for selective visualization of cyclooxygenase-2 in cancer cells
por: Pewklang, Thitima, et al.
Publicado: (2019)

A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A(2) on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A(2)α
por: Rodríguez, Juan P., et al.
Publicado: (2020)

Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models
por: Thotala, Dinesh, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_uqsh6n8isbvobe32bvq585gsj9