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Rhabdastrellic Acid-A Induced Autophagy-Associated Cell Death through Blocking Akt Pathway in Human Cancer Cells

BACKGROUND: Autophagy is an evolutionarily conserved protein degradation pathway. A defect in autophagy may contribute to tumorigenesis. Autophagy inducers could have a potential function in tumor prevention and treatment. METHODOLOGY/PRINCIPAL FINDINGS: Our results showed that Rhabdastrellic acid-A...

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Detalles Bibliográficos
Autores principales: Li, Dan-Dan, Guo, Jing-Feng, Huang, Jia-Jia, Wang, Lin-Lin, Deng, Rong, Liu, Jian-Nan, Feng, Gong-Kan, Xiao, Ding-Jun, Deng, Song-Zhi, Zhang, Xiao-Shi, Zhu, Xiao-Feng
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923153/
https://www.ncbi.nlm.nih.gov/pubmed/20808909
http://dx.doi.org/10.1371/journal.pone.0012176