Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report

INTRODUCTION: Guillain-Barré syndrome is an immune-mediated polyneuropathy that is routinely initially treated with either intravenous immunoglobulin or plasmapheresis. To the best of our knowledge, no association between plasmapheresis treatment and acute onset of facial neuropathy has been reporte...

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Autores principales: Stevenson, Mary L, Weimer, Louis H, Bogorad, Ilya V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923178/
https://www.ncbi.nlm.nih.gov/pubmed/20691080
http://dx.doi.org/10.1186/1752-1947-4-253
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author Stevenson, Mary L
Weimer, Louis H
Bogorad, Ilya V
author_facet Stevenson, Mary L
Weimer, Louis H
Bogorad, Ilya V
author_sort Stevenson, Mary L
collection PubMed
description INTRODUCTION: Guillain-Barré syndrome is an immune-mediated polyneuropathy that is routinely initially treated with either intravenous immunoglobulin or plasmapheresis. To the best of our knowledge, no association between plasmapheresis treatment and acute onset of facial neuropathy has been reported. CASE PRESENTATION: A 35-year-old Caucasian man with no significant prior medical history developed ascending motor weakness and laboratory findings consistent with a diagnosis of Guillain-Barré syndrome. Plasmapheresis was initiated. Acute facial palsy developed during the plasma exchange that subsequently resolved and then acutely recurred during the subsequent plasma exchange. CONCLUSION: To the best of our knowledge, no prior cases of acute facial palsy developing during plasmapheresis treatment are known. Although facial nerve involvement is common in typical Guillain-Barré syndrome, the temporal association with treatment, near-complete resolution and later recurrence support the association. The possible mechanism of plasmapheresis-induced worsening of peripheral nerve function in Guillain-Barré syndrome is unknown.
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spelling pubmed-29231782010-08-18 Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report Stevenson, Mary L Weimer, Louis H Bogorad, Ilya V J Med Case Reports Case Report INTRODUCTION: Guillain-Barré syndrome is an immune-mediated polyneuropathy that is routinely initially treated with either intravenous immunoglobulin or plasmapheresis. To the best of our knowledge, no association between plasmapheresis treatment and acute onset of facial neuropathy has been reported. CASE PRESENTATION: A 35-year-old Caucasian man with no significant prior medical history developed ascending motor weakness and laboratory findings consistent with a diagnosis of Guillain-Barré syndrome. Plasmapheresis was initiated. Acute facial palsy developed during the plasma exchange that subsequently resolved and then acutely recurred during the subsequent plasma exchange. CONCLUSION: To the best of our knowledge, no prior cases of acute facial palsy developing during plasmapheresis treatment are known. Although facial nerve involvement is common in typical Guillain-Barré syndrome, the temporal association with treatment, near-complete resolution and later recurrence support the association. The possible mechanism of plasmapheresis-induced worsening of peripheral nerve function in Guillain-Barré syndrome is unknown. BioMed Central 2010-08-06 /pmc/articles/PMC2923178/ /pubmed/20691080 http://dx.doi.org/10.1186/1752-1947-4-253 Text en Copyright ©2010 Stevenson et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Stevenson, Mary L
Weimer, Louis H
Bogorad, Ilya V
Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report
title Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report
title_full Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report
title_fullStr Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report
title_full_unstemmed Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report
title_short Development of recurrent facial palsy during plasmapheresis in Guillain-Barré syndrome: a case report
title_sort development of recurrent facial palsy during plasmapheresis in guillain-barré syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923178/
https://www.ncbi.nlm.nih.gov/pubmed/20691080
http://dx.doi.org/10.1186/1752-1947-4-253
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