The Impact of mRNA Structure on Guide RNA Targeting in Kinetoplastid RNA Editing

Mitochondrial mRNA editing in Trypanosoma brucei requires the specific interaction of a guide RNA with its cognate mRNA. Hundreds of gRNAs are involved in the editing process, each needing to target their specific editing domain within the target message. We hypothesized that the structure surroundi...

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Detalles Bibliográficos
Autores principales: Reifur, Larissa, Yu, Laura E., Cruz-Reyes, Jorge, vanHartesvelt, Michelle, Koslowsky, Donna J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923197/
https://www.ncbi.nlm.nih.gov/pubmed/20808932
http://dx.doi.org/10.1371/journal.pone.0012235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923197/
https://www.ncbi.nlm.nih.gov/pubmed/20808932
http://dx.doi.org/10.1371/journal.pone.0012235

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