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The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation

The temporal pole (TP) is the rostralmost portion of the human temporal lobe. Characteristically, it is only present in human and nonhuman primates. TP has been implicated in different cognitive functions such as emotion, attention, behavior, and memory, based on functional studies performed in heal...

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Autores principales: Blaizot, X., Mansilla, F., Insausti, A. M., Constans, J. M., Salinas-Alamán, A., Pró-Sistiaga, P., Mohedano-Moriano, A., Insausti, R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923216/
https://www.ncbi.nlm.nih.gov/pubmed/20064939
http://dx.doi.org/10.1093/cercor/bhp289
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author Blaizot, X.
Mansilla, F.
Insausti, A. M.
Constans, J. M.
Salinas-Alamán, A.
Pró-Sistiaga, P.
Mohedano-Moriano, A.
Insausti, R.
author_facet Blaizot, X.
Mansilla, F.
Insausti, A. M.
Constans, J. M.
Salinas-Alamán, A.
Pró-Sistiaga, P.
Mohedano-Moriano, A.
Insausti, R.
author_sort Blaizot, X.
collection PubMed
description The temporal pole (TP) is the rostralmost portion of the human temporal lobe. Characteristically, it is only present in human and nonhuman primates. TP has been implicated in different cognitive functions such as emotion, attention, behavior, and memory, based on functional studies performed in healthy controls and patients with neurodegenerative diseases through its anatomical connections (amygdala, pulvinar, orbitofrontal cortex). TP was originally described as a single uniform area by Brodmann area 38, and von Economo (area TG of von Economo and Koskinas), and little information on its cytoarchitectonics is known in humans. We hypothesize that 1) TP is not a homogenous area and we aim first at fixating the precise extent and limits of temporopolar cortex (TPC) with adjacent fields and 2) its structure can be correlated with structural magnetic resonance images. We describe here the macroscopic characteristics and cytoarchitecture as two subfields, a medial and a lateral area, that constitute TPC also noticeable in 2D and 3D reconstructions. Our findings suggest that the human TP is a heterogeneous region formed exclusively by TPC for about 7 mm of the temporal tip, and that becomes progressively restricted to the medial and ventral sides of the TP. This cortical area presents topographical and structural features in common with nonhuman primates, which suggests an evolutionary development in human species.
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spelling pubmed-29232162010-08-30 The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation Blaizot, X. Mansilla, F. Insausti, A. M. Constans, J. M. Salinas-Alamán, A. Pró-Sistiaga, P. Mohedano-Moriano, A. Insausti, R. Cereb Cortex Articles The temporal pole (TP) is the rostralmost portion of the human temporal lobe. Characteristically, it is only present in human and nonhuman primates. TP has been implicated in different cognitive functions such as emotion, attention, behavior, and memory, based on functional studies performed in healthy controls and patients with neurodegenerative diseases through its anatomical connections (amygdala, pulvinar, orbitofrontal cortex). TP was originally described as a single uniform area by Brodmann area 38, and von Economo (area TG of von Economo and Koskinas), and little information on its cytoarchitectonics is known in humans. We hypothesize that 1) TP is not a homogenous area and we aim first at fixating the precise extent and limits of temporopolar cortex (TPC) with adjacent fields and 2) its structure can be correlated with structural magnetic resonance images. We describe here the macroscopic characteristics and cytoarchitecture as two subfields, a medial and a lateral area, that constitute TPC also noticeable in 2D and 3D reconstructions. Our findings suggest that the human TP is a heterogeneous region formed exclusively by TPC for about 7 mm of the temporal tip, and that becomes progressively restricted to the medial and ventral sides of the TP. This cortical area presents topographical and structural features in common with nonhuman primates, which suggests an evolutionary development in human species. Oxford University Press 2010-09 2010-01-11 /pmc/articles/PMC2923216/ /pubmed/20064939 http://dx.doi.org/10.1093/cercor/bhp289 Text en © The Authors 2010. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Blaizot, X.
Mansilla, F.
Insausti, A. M.
Constans, J. M.
Salinas-Alamán, A.
Pró-Sistiaga, P.
Mohedano-Moriano, A.
Insausti, R.
The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation
title The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation
title_full The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation
title_fullStr The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation
title_full_unstemmed The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation
title_short The Human Parahippocampal Region: I. Temporal Pole Cytoarchitectonic and MRI Correlation
title_sort human parahippocampal region: i. temporal pole cytoarchitectonic and mri correlation
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923216/
https://www.ncbi.nlm.nih.gov/pubmed/20064939
http://dx.doi.org/10.1093/cercor/bhp289
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