A Combinatorial Approach for Targeted Delivery using Small Molecules and Reversible Masking to Bypass Non-Specific Uptake In Vivo

We have developed a multi-disciplinary approach combining molecular biology, delivery technology, combinatorial chemistry, and reversible masking to create improved systemic, targeted delivery of plasmid DNA while avoiding non-specific uptake in vivo. We initially used a well characterized model tar...

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Detalles Bibliográficos
Autores principales: Shi, Qiaoyun, Nguyen, Andrew T., Angell, Yu, Deng, Defeng, Na, Chang-Rim, Burgess, Kevin, Roberts, David D., Brunicardi, F. Charles, Templeton, Nancy Smyth
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923228/
https://www.ncbi.nlm.nih.gov/pubmed/20463761
http://dx.doi.org/10.1038/gt.2010.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923228/
https://www.ncbi.nlm.nih.gov/pubmed/20463761
http://dx.doi.org/10.1038/gt.2010.55

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