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Axonal inclusions in spinocerebellar ataxia type 3

Protein aggregation is a major pathological hallmark of many neurodegenerative disorders including polyglutamine diseases. Aggregation of the mutated form of the disease protein ataxin-3 into neuronal nuclear inclusions is well described in the polyglutamine disorder spinocerebellar ataxia type 3 (S...

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Detalles Bibliográficos
Autores principales: Seidel, Kay, den Dunnen, Wilfred F. A., Schultz, Christian, Paulson, Henry, Frank, Stefanie, de Vos, Rob A., Brunt, Ewout R., Deller, Thomas, Kampinga, Harm H., Rüb, Udo
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923324/
https://www.ncbi.nlm.nih.gov/pubmed/20635090
http://dx.doi.org/10.1007/s00401-010-0717-7