Cargando…

Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice

Degeneration of motor neurons contributes to senescence-associated loss of muscle function and underlies human neurodegenerative conditions such as amyotrophic lateral sclerosis and spinal muscular atrophy. The identification of genetic factors contributing to motor neuron vulnerability and degenera...

Descripción completa

Detalles Bibliográficos
Autores principales: de Waard, Monique C., van der Pluijm, Ingrid, Zuiderveen Borgesius, Nils, Comley, Laura H., Haasdijk, Elize D., Rijksen, Yvonne, Ridwan, Yanto, Zondag, Gerben, Hoeijmakers, Jan H. J., Elgersma, Ype, Gillingwater, Thomas H., Jaarsma, Dick
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923326/
https://www.ncbi.nlm.nih.gov/pubmed/20602234
http://dx.doi.org/10.1007/s00401-010-0715-9