DNA Polymerases β and λ Mediate Overlapping and Independent Roles in Base Excision Repair in Mouse Embryonic Fibroblasts

Base excision repair (BER) is a DNA repair pathway designed to correct small base lesions in genomic DNA. While DNA polymerase beta (pol β) is known to be the main polymerase in the BER pathway, various studies have implicated other DNA polymerases in back-up roles. One such polymerase, DNA polymera...

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Detalles Bibliográficos
Autores principales: Braithwaite, Elena K., Kedar, Padmini S., Stumpo, Deborah J., Bertocci, Barbara, Freedman, Jonathan H., Samson, Leona D., Wilson, Samuel H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923601/
https://www.ncbi.nlm.nih.gov/pubmed/20805875
http://dx.doi.org/10.1371/journal.pone.0012229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923601/
https://www.ncbi.nlm.nih.gov/pubmed/20805875
http://dx.doi.org/10.1371/journal.pone.0012229

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