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Apparent Non-Canonical Trans-Splicing Is Generated by Reverse Transcriptase In Vitro

BACKGROUND: Trans-splicing, the in vivo joining of two independently transcribed RNA molecules, is well characterized in lower eukaryotes, but was long thought absent from metazoans. However, recent bioinformatic analyses of EST sequences suggested widespread trans-splicing in mammals. These apparen...

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Detalles Bibliográficos
Autores principales: Houseley, Jonathan, Tollervey, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923612/
https://www.ncbi.nlm.nih.gov/pubmed/20805885
http://dx.doi.org/10.1371/journal.pone.0012271