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Persistence of Different Forms of Transient RNAi during Apoptosis in Mammalian Cells

Gene silencing by transient or stable RNA-interference (RNAi) is used for the study of apoptosis with an assumption that apoptotic events will not influence RNAi. However, we recently reported that stable RNAi, i.e., a permanent gene-knockdown mediated by shRNA-generating DNA vectors that are integr...

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Detalles Bibliográficos
Autores principales: Kandan-Kulangara, Febitha, Shah, Rashmi G., Affar, El Bachir, Shah, Girish M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923616/
https://www.ncbi.nlm.nih.gov/pubmed/20805889
http://dx.doi.org/10.1371/journal.pone.0012263