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Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis, radiosensitization, and overcomes temozolomide resistance in malignant gliomas
High-grade gliomas are among the most lethal of all cancers. Despite considerable advances in multi-modality treatment, including surgery, radiotherapy, and chemotherapy, the overall prognosis for patients with this disease remains dismal. Currently available treatments necessitate the development o...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923667/ https://www.ncbi.nlm.nih.gov/pubmed/20523363 http://dx.doi.org/10.1038/cgt.2010.31 |