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Aldosterone Modulates Cell Proliferation and Apoptosis in the Neonatal Rat Heart

In the present study, we investigated whether and how the mineralocorticoid receptor antagonist spironolactone affects cardiac growth and development through apoptosis and cell proliferation in the neonatal rat heart. Newborn rat pups were treated with spironolactone (200 mg/kg/d) for 7 days. The ce...

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Detalles Bibliográficos
Autores principales: Sohn, Hyung Joo, Yoo, Kee Hwan, Jang, Gi Young, Lee, Jang Hoon, Choi, Byung Min, Lee, Jung Hwa, Bae, In Sun, Yim, Hyung Eun, Son, Chang Sung, Lee, Joo Won
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923799/
https://www.ncbi.nlm.nih.gov/pubmed/20808672
http://dx.doi.org/10.3346/jkms.2010.25.9.1296