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Recognition of Polyadenosine RNA by the Zinc Finger Domain of Nuclear Poly(A) RNA-binding Protein 2 (Nab2) Is Required for Correct mRNA 3′-End Formation*

Proteins bound to the poly(A) tail of mRNA transcripts, called poly(A)-binding proteins (Pabs), play critical roles in regulating RNA stability, translation, and nuclear export. Like many mRNA-binding proteins that modulate post-transcriptional processing events, assigning specific functions to Pabs...

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Detalles Bibliográficos
Autores principales: Kelly, Seth M., Leung, Sara W., Apponi, Luciano H., Bramley, Anna M., Tran, Elizabeth J., Chekanova, Julia A., Wente, Susan R., Corbett, Anita H.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924000/
https://www.ncbi.nlm.nih.gov/pubmed/20554526
http://dx.doi.org/10.1074/jbc.M110.141127