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The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres

BACKGROUND: Recent evidence suggests that epithelial cancers, including colorectal cancer are driven by a small sub-population of self-renewing, multi-potent cells termed cancer stem cells (CSCs) which are thought to be responsible for recurrence of cancer. One of the characteristics of CSCs is thei...

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Detalles Bibliográficos
Autores principales: Kanwar, Shailender S, Yu, Yingjie, Nautiyal, Jyoti, Patel, Bhaumik B, Majumdar, Adhip PN
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924313/
https://www.ncbi.nlm.nih.gov/pubmed/20691072
http://dx.doi.org/10.1186/1476-4598-9-212