Peptides derived from the HIV-1 integrase promote HIV-1 infection and multi-integration of viral cDNA in LEDGF/p75-knockdown cells

BACKGROUND: The presence of the cellular Lens Epithelium Derived Growth Factor p75 (LEDGF/p75) protein is essential for integration of the Human immunodeficiency virus type 1 (HIV-1) cDNA and for efficient virus production. In the absence of LEDGF/p75 very little integration and virus production can...

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Detalles Bibliográficos
Autores principales: Levin, Aviad, Hayouka, Zvi, Friedler, Assaf, Loyter, Abraham
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924314/
https://www.ncbi.nlm.nih.gov/pubmed/20678206
http://dx.doi.org/10.1186/1743-422X-7-177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924314/
https://www.ncbi.nlm.nih.gov/pubmed/20678206
http://dx.doi.org/10.1186/1743-422X-7-177

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