Disease-Associated Mutations That Alter the RNA Structural Ensemble

Genome-wide association studies (GWAS) often identify disease-associated mutations in intergenic and non-coding regions of the genome. Given the high percentage of the human genome that is transcribed, we postulate that for some observed associations the disease phenotype is caused by a structural r...

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Detalles Bibliográficos
Autores principales: Halvorsen, Matthew, Martin, Joshua S., Broadaway, Sam, Laederach, Alain
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924325/
https://www.ncbi.nlm.nih.gov/pubmed/20808897
http://dx.doi.org/10.1371/journal.pgen.1001074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924325/
https://www.ncbi.nlm.nih.gov/pubmed/20808897
http://dx.doi.org/10.1371/journal.pgen.1001074

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