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Enterohemorrhagic E. coli Requires N-WASP for Efficient Type III Translocation but Not for EspF(U)-Mediated Actin Pedestal Formation
Upon infection of mammalian cells, enterohemorrhagic E. coli (EHEC) O157:H7 utilizes a type III secretion system to translocate the effectors Tir and EspF(U) (aka TccP) that trigger the formation of F-actin-rich ‘pedestals’ beneath bound bacteria. EspF(U) is localized to the plasma membrane by Tir a...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924363/ https://www.ncbi.nlm.nih.gov/pubmed/20808845 http://dx.doi.org/10.1371/journal.ppat.1001056 |