Regulatory T Cells Suppress Natural Killer Cells during Plasmid DNA Vaccination in Mice, Blunting the CD8(+) T Cell Immune Response by the Cytokine TGFβ

BACKGROUND: CD4(+)CD25(+) regulatory T cells (Tregs) suppress adaptive T cell-mediated immune responses to self- and foreign-antigens. Tregs may also suppress early innate immune responses to vaccine antigens and might decrease vaccine efficacy. NK and NKT cells are the first responders after plasmi...

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Detalles Bibliográficos
Autores principales: Frimpong-Boateng, Kwesi, van Rooijen, Nico, Geiben-Lynn, Ralf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924372/
https://www.ncbi.nlm.nih.gov/pubmed/20808850
http://dx.doi.org/10.1371/journal.pone.0012281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924372/
https://www.ncbi.nlm.nih.gov/pubmed/20808850
http://dx.doi.org/10.1371/journal.pone.0012281

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