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Insights into the Mechanism of Ligand Binding to Octopine Dehydrogenase from Pecten maximus by NMR and Crystallography

Octopine dehydrogenase (OcDH) from the adductor muscle of the great scallop, Pecten maximus, catalyzes the NADH dependent, reductive condensation of L-arginine and pyruvate to octopine, NAD(+), and water during escape swimming and/or subsequent recovery. The structure of OcDH was recently solved and...

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Detalles Bibliográficos
Autores principales: Smits, Sander H. J., Meyer, Tatu, Mueller, Andre, van Os, Nadine, Stoldt, Matthias, Willbold, Dieter, Schmitt, Lutz, Grieshaber, Manfred K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924402/
https://www.ncbi.nlm.nih.gov/pubmed/20808820
http://dx.doi.org/10.1371/journal.pone.0012312