Spinophilin directs Protein Phosphatase 1 specificity by blocking substrate binding sites

The serine/threonine Protein Phosphatase 1 (PP1) dephosphorylates hundreds of key biological targets. PP1 associates with ≥200 regulatory proteins to form highly specific holoenzymes. These regulatory proteins target PP1 to its point of action within the cell and prime its enzymatic specificity for...

Descripción completa

Detalles Bibliográficos
Autores principales: Ragusa, Michael J., Dancheck, Barbara, Critton, David A., Nairn, Angus C., Page, Rebecca, Peti, Wolfgang
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924587/
https://www.ncbi.nlm.nih.gov/pubmed/20305656
http://dx.doi.org/10.1038/nsmb.1786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924587/
https://www.ncbi.nlm.nih.gov/pubmed/20305656
http://dx.doi.org/10.1038/nsmb.1786

Ejemplares similares