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Spinophilin directs Protein Phosphatase 1 specificity by blocking substrate binding sites

The serine/threonine Protein Phosphatase 1 (PP1) dephosphorylates hundreds of key biological targets. PP1 associates with ≥200 regulatory proteins to form highly specific holoenzymes. These regulatory proteins target PP1 to its point of action within the cell and prime its enzymatic specificity for...

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Detalles Bibliográficos
Autores principales:	Ragusa, Michael J., Dancheck, Barbara, Critton, David A., Nairn, Angus C., Page, Rebecca, Peti, Wolfgang
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924587/ https://www.ncbi.nlm.nih.gov/pubmed/20305656 http://dx.doi.org/10.1038/nsmb.1786

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