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Antigen quality determines the efficiency of antitumor immune responses generated in the absence of regulatory T cells

The observation that depletion or inhibition of regulatory T cells (Tregs) unleashes efficient antitumor effector immune responses that can lead to tumor eradication in mice has opened new perspectives for the development of cancer immunotherapy. The quality and overall efficiency of the effector im...

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Detalles Bibliográficos
Autores principales: Bergot, A-S, Durgeau, A, Levacher, B, Colombo, B M, Cohen, J L, Klatzmann, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924606/
https://www.ncbi.nlm.nih.gov/pubmed/20467452
http://dx.doi.org/10.1038/cgt.2010.21