Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells

BACKGROUND: Src family kinases (SFK) collectively regulate a variety of cellular functions in many cancer types, including proliferation, invasion, motility, survival, differentiation, and angiogenesis. Although Dasatinib (BMS-354825), an ATP-competitive, small molecule tyrosine kinase inhibitor, su...

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Detalles Bibliográficos
Autores principales: Premkumar, Daniel R., Jane, Esther P., Agostino, Naomi R., Scialabba, Joseph L., Pollack, Ian F.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924609/
https://www.ncbi.nlm.nih.gov/pubmed/20808823
http://dx.doi.org/10.4103/1477-3163.65448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924609/
https://www.ncbi.nlm.nih.gov/pubmed/20808823
http://dx.doi.org/10.4103/1477-3163.65448

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