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Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells

BACKGROUND: Src family kinases (SFK) collectively regulate a variety of cellular functions in many cancer types, including proliferation, invasion, motility, survival, differentiation, and angiogenesis. Although Dasatinib (BMS-354825), an ATP-competitive, small molecule tyrosine kinase inhibitor, su...

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Detalles Bibliográficos
Autores principales:	Premkumar, Daniel R., Jane, Esther P., Agostino, Naomi R., Scialabba, Joseph L., Pollack, Ian F.
Formato:	Texto
Lenguaje:	English
Publicado:	Medknow Publications 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924609/ https://www.ncbi.nlm.nih.gov/pubmed/20808823 http://dx.doi.org/10.4103/1477-3163.65448

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