Potent Delivery of Functional Proteins into Mammalian Cells in Vitro and in Vivo Using a Supercharged Protein

[Image: see text] The inability of proteins to potently penetrate mammalian cells limits their usefulness as tools and therapeutics. When fused to superpositively charged GFP, proteins rapidly (within minutes) entered five different types of mammalian cells with potency up to ∼100-fold greater than...

Descripción completa

Detalles Bibliográficos
Autores principales: Cronican, James J., Thompson, David B., Beier, Kevin T., McNaughton, Brian R., Cepko, Constance L., Liu, David R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924640/
https://www.ncbi.nlm.nih.gov/pubmed/20545362
http://dx.doi.org/10.1021/cb1001153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924640/
https://www.ncbi.nlm.nih.gov/pubmed/20545362
http://dx.doi.org/10.1021/cb1001153

Ejemplares similares