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Role of neuropeptides, hormones, and growth factors in regulating thymopoiesis in middle to old age

The deterioration in adaptive immunity and T-lymphocyte output and the narrowing of the T cell receptor repertoire with age are largely attributable to thymic involution. The loss of thymic function with age may be due to diminished numbers of early thymic progenitors and epithelial cells, and the l...

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Detalles Bibliográficos
Autores principales: Patel, Kalpesh, Taub, Dennis D
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924688/
https://www.ncbi.nlm.nih.gov/pubmed/20948643
http://dx.doi.org/10.3410/B1-42