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B cell-targeted therapies in autoimmunity: rationale and progress

B cells are recognized as main actors in the autoimmune process. Autoreactive B cells can arise in the bone marrow or in the periphery and, if not properly inhibited or eliminated, can lead to autoimmune diseases through several mechanisms: autoantibody production and immune complex formation, cytok...

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Detalles Bibliográficos
Autores principales: Fiorina, Paolo, Sayegh, Mohamed H
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924700/
https://www.ncbi.nlm.nih.gov/pubmed/20948646
http://dx.doi.org/10.3410/B1-39