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B cell-targeted therapies in autoimmunity: rationale and progress
B cells are recognized as main actors in the autoimmune process. Autoreactive B cells can arise in the bone marrow or in the periphery and, if not properly inhibited or eliminated, can lead to autoimmune diseases through several mechanisms: autoantibody production and immune complex formation, cytok...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Biology Reports Ltd
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924700/ https://www.ncbi.nlm.nih.gov/pubmed/20948646 http://dx.doi.org/10.3410/B1-39 |