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Two negative randomized controlled trials in lupus: now what?

Recently, two large randomized controlled trials of distinct biologic therapies in systemic lupus erythematosus, B-cell depletion with rituximab and co-stimulatory blockade with CTLA4Ig (abatacept), failed to meet primary endpoints. Given the great need for new treatments in lupus, these results wer...

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Detalles Bibliográficos
Autores principales: Coca, Andreea, Anolik, Jennifer H
Formato: Texto
Lenguaje:English
Publicado: Medicine Reports Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924714/
https://www.ncbi.nlm.nih.gov/pubmed/20948753
http://dx.doi.org/10.3410/M1-28