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PKCα-induced drug resistance in pancreatic cancer cells is associated with transforming growth factor-β1

BACKGROUND: Drug resistance remains a great challenge in the treatment of pancreatic cancer. The goal of this study was to determine whether TGF-β1 is associated with drug resistance in pancreatic cancer. METHODS: Pancreatic cancer BxPC3 cells were stably transfected with TGF-β1 cDNA. Cellular morph...

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Detalles Bibliográficos
Autores principales:	Chen, Ying, Yu, Guanzhen, Yu, Danghui, Zhu, Minghua
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924847/ https://www.ncbi.nlm.nih.gov/pubmed/20684793 http://dx.doi.org/10.1186/1756-9966-29-104

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