Frequent associations between CTL and T-Helper epitopes in HIV-1 genomes and implications for multi-epitope vaccine designs

BACKGROUND: Epitope vaccines have been suggested as a strategy to counteract viral escape and development of drug resistance. Multiple studies have shown that Cytotoxic T-Lymphocyte (CTL) and T-Helper (Th) epitopes can generate strong immune responses in Human Immunodeficiency Virus (HIV-1). However...

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Detalles Bibliográficos
Autores principales: Paul, Sinu, Piontkivska, Helen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924856/
https://www.ncbi.nlm.nih.gov/pubmed/20696039
http://dx.doi.org/10.1186/1471-2180-10-212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924856/
https://www.ncbi.nlm.nih.gov/pubmed/20696039
http://dx.doi.org/10.1186/1471-2180-10-212

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