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DNA-Triggered Aggregation of Copper, Zinc Superoxide Dismutase in the Presence of Ascorbate

The oxidative damage hypothesis proposed for the function gain of copper, zinc superoxide dismutase (SOD1) maintains that both mutant and wild-type (WT) SOD1 catalyze reactions with abnormal substrates that damage cellular components critical for viability of the affected cells. However, whether the...

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Detalles Bibliográficos
Autores principales: Yin, Jun, Hu, Si, Jiang, Wei, Liu, Liang, Lan, Shemin, Song, Xuegang, Liu, Changlin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924893/
https://www.ncbi.nlm.nih.gov/pubmed/20808835
http://dx.doi.org/10.1371/journal.pone.0012328