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DNA-Triggered Aggregation of Copper, Zinc Superoxide Dismutase in the Presence of Ascorbate
The oxidative damage hypothesis proposed for the function gain of copper, zinc superoxide dismutase (SOD1) maintains that both mutant and wild-type (WT) SOD1 catalyze reactions with abnormal substrates that damage cellular components critical for viability of the affected cells. However, whether the...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924893/ https://www.ncbi.nlm.nih.gov/pubmed/20808835 http://dx.doi.org/10.1371/journal.pone.0012328 |