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Loss of Pluripotency in Human Embryonic Stem Cells Directly Correlates with an Increase in Nuclear Zinc

The pluripotency of human embryonic stem cells (hESCs) is important to investigations of early development and to cell replacement therapy, but the mechanism behind pluripotency is incompletely understood. Zinc has been shown to play a key role in differentiation of non-pluripotent cell types, but h...

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Detalles Bibliográficos
Autores principales: Wolford, Janet L., Chishti, Yasmin, Jin, Qiaoling, Ward, Jesse, Chen, Liaohai, Vogt, Stefan, Finney, Lydia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924898/
https://www.ncbi.nlm.nih.gov/pubmed/20808840
http://dx.doi.org/10.1371/journal.pone.0012308