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The opening of the two pores of the Hv1 voltage-gated proton channel is tuned by cooperativity

In voltage-gated sodium, potassium, and calcium channels the functions of ion conduction and voltage sensing are performed by two distinct structural units: the pore domain and the voltage-sensing domain (VSD). In the Hv1 voltage-gated proton channel, the VSD has the remarkable property of performin...

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Detalles Bibliográficos
Autores principales: Tombola, Francesco, Ulbrich, Maximilian H., Kohout, Susy C., Isacoff, Ehud Y.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925041/
https://www.ncbi.nlm.nih.gov/pubmed/20023640
http://dx.doi.org/10.1038/nsmb.1738