Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis

OBJECTIVE: To evaluate the decrease of cartilage destruction by a novel orally active and specific matrix metalloproteinase 13 (MMP-13) inhibitor in three different animal models of rheumatoid arthritis (RA). MATERIALS AND METHODS: The SCID mouse co-implantation model of RA, the collagen-induced art...

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Detalles Bibliográficos
Autores principales: Jüngel, Astrid, Ospelt, Caroline, Lesch, Mark, Thiel, Melissa, Sunyer, Teresa, Schorr, Olivier, Michel, Beat A, Gay, Renate E, Kolling, Christoph, Flory, Craig, Gay, Steffen, Neidhart, Michel
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2009
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925150/
https://www.ncbi.nlm.nih.gov/pubmed/19497915
http://dx.doi.org/10.1136/ard.2008.106021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925150/
https://www.ncbi.nlm.nih.gov/pubmed/19497915
http://dx.doi.org/10.1136/ard.2008.106021

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