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Autophagy protein ATG5 interacts transiently with the hepatitis C virus RNA polymerase (NS5B) early during infection

Autophagy is an important cellular process by which ATG5 initiates the formation of double membrane vesicles (DMVs). Upon infection, DMVs have been shown to harbor the replicase complex of positive-strand RNA viruses such as MHV, poliovirus, and equine arteritis virus. Recently, it has been shown th...

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Detalles Bibliográficos
Autores principales: Guévin, Carl, Manna, David, Bélanger, Claudia, Konan, Kouacou V., Mak, Paul, Labonté, Patrick
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925245/
https://www.ncbi.nlm.nih.gov/pubmed/20580051
http://dx.doi.org/10.1016/j.virol.2010.05.032