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Effects of Immunomodulatory Substances on Phagocytosis of Aβ (1–42) by Human Microglia

Glial activation and increased inflammation characterize neuropathology in Alzheimer's disease (AD). The aim was to develop a model for studying phagocytosis of β-amyloid (Aβ) peptide by human microglia and to test effects thereupon by immunomodulatory substances. Human CHME3 microglia showed i...

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Detalles Bibliográficos
Autores principales: Hjorth, Erik, Frenkel, Dan, Weiner, Howard, Schultzberg, Marianne
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925296/
https://www.ncbi.nlm.nih.gov/pubmed/20798889
http://dx.doi.org/10.4061/2010/798424