Stimulation of DNA Glycosylase Activities by XPC Protein Complex: Roles of Protein-Protein Interactions

We showed that XPC complex, which is a DNA damage detector for nucleotide excision repair, stimulates activity of thymine DNA glycosylase (TDG) that initiates base excision repair. XPC appeared to facilitate the enzymatic turnover of TDG by promoting displacement from its own product abasic site, al...

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Detalles Bibliográficos
Autores principales: Shimizu, Yuichiro, Uchimura, Yasuhiro, Dohmae, Naoshi, Saitoh, Hisato, Hanaoka, Fumio, Sugasawa, Kaoru
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925305/
https://www.ncbi.nlm.nih.gov/pubmed/20798892
http://dx.doi.org/10.4061/2010/805698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925305/
https://www.ncbi.nlm.nih.gov/pubmed/20798892
http://dx.doi.org/10.4061/2010/805698

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