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Crystal structure of the α(6)β(6) holoenzyme of propionyl-coenzyme A carboxylase

Propionyl-coenzyme A carboxylase (PCC), a mitochondrial biotin-dependent enzyme, is essential for the catabolism of the amino acids Thr, Val, Ile and Met, cholesterol, and fatty acids with an odd number of carbon atoms. Deficiencies of PCC activity in humans are linked to the disease propionic acide...

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Detalles Bibliográficos
Autores principales: Huang, Christine S., Sadre-Bazzaz, Kianoush, Shen, Yang, Deng, Binbin, Zhou, Z. Hong, Tong, Liang
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925307/
https://www.ncbi.nlm.nih.gov/pubmed/20725044
http://dx.doi.org/10.1038/nature09302