Cargando…

Crystal structure of the α(6)β(6) holoenzyme of propionyl-coenzyme A carboxylase

Propionyl-coenzyme A carboxylase (PCC), a mitochondrial biotin-dependent enzyme, is essential for the catabolism of the amino acids Thr, Val, Ile and Met, cholesterol, and fatty acids with an odd number of carbon atoms. Deficiencies of PCC activity in humans are linked to the disease propionic acide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Christine S., Sadre-Bazzaz, Kianoush, Shen, Yang, Deng, Binbin, Zhou, Z. Hong, Tong, Liang
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925307/ https://www.ncbi.nlm.nih.gov/pubmed/20725044 http://dx.doi.org/10.1038/nature09302

Ejemplares similares

Structure and substrate selectivity of the 750-kDa α(6)β(6) holoenzyme of geranyl-CoA carboxylase
por: Jurado, Ashley R., et al.
Publicado: (2015)

Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
por: Wei, Jia, et al.
Publicado: (2015)

An unanticipated architecture of the 750 kD holoenzyme of 3-methylcrotonyl-CoA carboxylase
por: Huang, Christine S., et al.
Publicado: (2011)

A distinct holoenzyme organization for two-subunit pyruvate carboxylase
por: Choi, Philip H., et al.
Publicado: (2016)

A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation
por: Wei, Jia, et al.
Publicado: (2016)

A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation
por: Wei, Jia, et al.
Publicado: (2017)

Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli
por: Vandova, Gergana A, et al.
Publicado: (2017)

Generation of isogenic Propionyl-CoA carboxylase beta subunit (PCCB) deficient induced pluripotent stem cell lines
por: Pournasr, Behshad, et al.
Publicado: (2020)

Increasing the Ascomycin Yield by Relieving the Inhibition of Acetyl/Propionyl-CoA Carboxylase by the Signal Transduction Protein GlnB
por: Wang, Pan, et al.
Publicado: (2021)

Regulation of Trypanosoma brucei Acetyl Coenzyme A Carboxylase by Environmental Lipids
por: Ray, Sunayan S., et al.
Publicado: (2018)

Abundance and distribution of archaeal acetyl-CoA/propionyl-CoA carboxylase genes indicative for putatively chemoautotrophic Archaea in the tropical Atlantic's interior
por: Bergauer, Kristin, et al.
Publicado: (2013)

Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer
por: Maderbocus, Riyaz, et al.
Publicado: (2017)

The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini
por: Demirev, Atanas V., et al.
Publicado: (2010)

The architecture of Tetrahymena telomerase holoenzyme
por: Jiang, Jiansen, et al.
Publicado: (2013)

Determination of HIF-1α degradation pathways via modulation of the propionyl mark
por: Jeong, Kwanyoung, et al.
Publicado: (2023)

Deficient histone H3 propionylation by BRPF1-KAT6 complexes in neurodevelopmental disorders and cancer
por: Yan, Kezhi, et al.
Publicado: (2020)

Correction to: Crystal structure of PKG Iβ holoenzyme reveals a trans‑inhibiting dimer assembly
por: Kim, Choel, et al.
Publicado: (2020)

A Transfer Learning-Based Approach for Lysine Propionylation Prediction
por: Li, Ang, et al.
Publicado: (2021)

Mechanism of metamifop inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in Echinochloa crus-galli
por: Xia, Xiangdong, et al.
Publicado: (2016)

Maternal 3-methylcrotonyl-coenzyme A carboxylase deficiency with elevated 3-hydroxyisovalerylcarnitine in breast milk
por: Cho, Kyung Lae, et al.
Publicado: (2016)

Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme
por: Zhang, Ping, et al.
Publicado: (2015)

CRISPR Interference Reveals That All-Trans-Retinoic Acid Promotes Macrophage Control of Mycobacterium tuberculosis by Limiting Bacterial Access to Cholesterol and Propionyl Coenzyme A
por: Babunovic, Gregory H., et al.
Publicado: (2022)

Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis
por: Dou, Chao, et al.
Publicado: (2022)

Targeting host metabolism by inhibition of acetyl-Coenzyme A carboxylase reduces flavivirus infection in mouse models
por: Jiménez de Oya, Nereida, et al.
Publicado: (2019)

The β Subunit of the Na(+)/K(+)-ATPase Follows the Conformational State of the Holoenzyme
por: Dempski, Robert E., et al.
Publicado: (2005)

Regulation of PP2A, PP4, and PP6 holoenzyme assembly by carboxyl-terminal methylation
por: Lyons, Scott P., et al.
Publicado: (2021)

Crystal structures of phosphine-supported (η(5)-cyclopentadienyl)molybdenum(II) propionyl complexes
por: Whited, Matthew T., et al.
Publicado: (2021)

Cone Phosphodiesterase-6γ’ Subunit Augments Cone PDE6 Holoenzyme Assembly and Stability in a Mouse Model Lacking Both Rod and Cone PDE6 Catalytic Subunits
por: Deng, Wen-Tao, et al.
Publicado: (2018)

Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme
por: Cliffe, Rachel, et al.
Publicado: (2019)

Organization of an Activator-Bound RNA Polymerase Holoenzyme
por: Bose, Daniel, et al.
Publicado: (2008)

Stepwise assembly of the human replicative polymerase holoenzyme
por: Hedglin, Mark, et al.
Publicado: (2013)

Structure of the processive human Pol δ holoenzyme
por: Lancey, Claudia, et al.
Publicado: (2020)

Pitfalls in histone propionylation during bottom‐up mass spectrometry analysis
por: Meert, Paulien, et al.
Publicado: (2015)

Small-sample learning reveals propionylation in determining global protein homeostasis
por: Shui, Ke, et al.
Publicado: (2023)

Fitness costs associated with acetyl‐coenzyme A carboxylase mutations endowing herbicide resistance in American sloughgrass (Beckmannia syzigachne Steud.)
por: Du, Long, et al.
Publicado: (2019)

The unique Phe–His dyad of 2-ketopropyl coenzyme M oxidoreductase/carboxylase selectively promotes carboxylation and S–C bond cleavage
por: Prussia, Gregory A., et al.
Publicado: (2021)

A catalytic dyad modulates conformational change in the CO(2)-fixing flavoenzyme 2-ketopropyl coenzyme M oxidoreductase/carboxylase
por: Mattice, Jenna R., et al.
Publicado: (2022)

Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation
por: Cook, Sarah G., et al.
Publicado: (2018)

Coenzyme Q10 suppresses apoptosis of mouse pancreatic β-cell line MIN6
por: Sumi, Keisuke, et al.
Publicado: (2018)

A Single Nucleotide Polymorphism within the Acetyl-Coenzyme A Carboxylase Beta Gene Is Associated with Proteinuria in Patients with Type 2 Diabetes
por: Maeda, Shiro, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_vq596nesg4ck064c60oneqslha