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Effects of mitochondrial dysfunction on the immunological properties of microglia

BACKGROUND: Neurodegenerative diseases are characterized by both mitochondrial dysfunction and activation of microglia, the macrophages of the brain. Here, we investigate the effects of mitochondrial dysfunction on the activation profile of microglial cells. METHODS: We incubated primary mouse micro...

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Detalles Bibliográficos
Autores principales: Ferger, Annette I, Campanelli, Loretta, Reimer, Valentina, Muth, Katharina N, Merdian, Irma, Ludolph, Albert C, Witting, Anke
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925359/
https://www.ncbi.nlm.nih.gov/pubmed/20701773
http://dx.doi.org/10.1186/1742-2094-7-45