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Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta

Understanding polymerase fidelity is an important objective towards ascertaining the overall stability of an organism's genome. Saccharomyces cerevisiae DNA polymerase η (yPolη), a Y-family DNA polymerase, is known to efficiently bypass DNA lesions (e.g., pyrimidine dimers) in vivo. Using pre-s...

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Detalles Bibliográficos
Autores principales: Brown, Jessica A., Zhang, Likui, Sherrer, Shanen M., Taylor, John-Stephen, Burgers, Peter M. J., Suo, Zucai
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925389/
https://www.ncbi.nlm.nih.gov/pubmed/20798853
http://dx.doi.org/10.4061/2010/871939