Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)

BACKGROUND: Collagen, a triple-helical, self-organizing protein, is the predominant structural protein in mammals. It is found in bone, ligament, tendon, cartilage, intervertebral disc, skin, blood vessel, and cornea. We have recently postulated that fibrillar collagens (and their complementary enzy...

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Detalles Bibliográficos
Autores principales: Flynn, Brendan P., Bhole, Amit P., Saeidi, Nima, Liles, Melody, DiMarzio, Charles A., Ruberti, Jeffrey W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925882/
https://www.ncbi.nlm.nih.gov/pubmed/20808784
http://dx.doi.org/10.1371/journal.pone.0012337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925882/
https://www.ncbi.nlm.nih.gov/pubmed/20808784
http://dx.doi.org/10.1371/journal.pone.0012337

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