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Mechanical Strain Stabilizes Reconstituted Collagen Fibrils against Enzymatic Degradation by Mammalian Collagenase Matrix Metalloproteinase 8 (MMP-8)
BACKGROUND: Collagen, a triple-helical, self-organizing protein, is the predominant structural protein in mammals. It is found in bone, ligament, tendon, cartilage, intervertebral disc, skin, blood vessel, and cornea. We have recently postulated that fibrillar collagens (and their complementary enzy...
Autores principales: | Flynn, Brendan P., Bhole, Amit P., Saeidi, Nima, Liles, Melody, DiMarzio, Charles A., Ruberti, Jeffrey W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925882/ https://www.ncbi.nlm.nih.gov/pubmed/20808784 http://dx.doi.org/10.1371/journal.pone.0012337 |
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