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Structural Basis for Certain Naturally Occurring Bioflavonoids to Function as Reducing Co-Substrates of Cyclooxygenase I and II

BACKGROUND: Recent studies showed that some of the dietary bioflavonoids can strongly stimulate the catalytic activity of cyclooxygenase (COX) I and II in vitro and in vivo, presumably by facilitating enzyme re-activation. In this study, we sought to understand the structural basis of COX activation...

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Detalles Bibliográficos
Autores principales: Wang, Pan, Bai, Hyoung-Woo, Zhu, Bao Ting
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925883/
https://www.ncbi.nlm.nih.gov/pubmed/20808785
http://dx.doi.org/10.1371/journal.pone.0012316