A Structure-Based Approach for Mapping Adverse Drug Reactions to the Perturbation of Underlying Biological Pathways

Adverse drug reactions (ADR), also known as side-effects, are complex undesired physiologic phenomena observed secondary to the administration of pharmaceuticals. Several phenomena underlie the emergence of each ADR; however, a dominant factor is the drug's ability to modulate one or more biolo...

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Detalles Bibliográficos
Autores principales: Wallach, Izhar, Jaitly, Navdeep, Lilien, Ryan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925884/
https://www.ncbi.nlm.nih.gov/pubmed/20808786
http://dx.doi.org/10.1371/journal.pone.0012063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925884/
https://www.ncbi.nlm.nih.gov/pubmed/20808786
http://dx.doi.org/10.1371/journal.pone.0012063

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