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Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes

PURPOSE: We have previously shown that non-psychotropic cannabidiol (CBD) protects retinal neurons in diabetic rats by inhibiting reactive oxygen species and blocking tyrosine nitration. Tyrosine nitration may inhibit glutamine synthetase (GS), causing glutamate accumulation and leading to further n...

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Detalles Bibliográficos
Autores principales: El-Remessy, A.B., Khalifa, Y., Ola, S., Ibrahim, A.S., Liou, G.I.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925907/
https://www.ncbi.nlm.nih.gov/pubmed/20806080