Deletion of Nhlh2 Results in a Defective Torpor Response and Reduced Beta Adrenergic Receptor Expression in Adipose Tissue

BACKGROUND: Mice with a targeted deletion of the basic helix-loop-helix transcription factor, Nescient Helix-Loop-Helix 2 (Nhlh2), display adult-onset obesity with significant increases in their fat depots, abnormal responses to cold exposure, and reduced spontaneous physical activity levels. These...

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Detalles Bibliográficos
Autores principales: Wankhade, Umesh D., Vella, Kristen R., Fox, Dana L., Good, Deborah J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925948/
https://www.ncbi.nlm.nih.gov/pubmed/20808804
http://dx.doi.org/10.1371/journal.pone.0012324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925948/
https://www.ncbi.nlm.nih.gov/pubmed/20808804
http://dx.doi.org/10.1371/journal.pone.0012324

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