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MicroRNAs modulate the noncanonical NF-κB pathway by regulating IKKα expression during macrophage differentiation

MicroRNAs are key regulators in many biological processes including cell differentiation. Here we show that during human monocyte-macrophage differentiation, the expression of the microRNAs miR-223, miR-15a, and miR-16 is dramatically decreased, leading to increased expression of the serine-threonin...

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Detalles Bibliográficos
Autores principales: Li, Tao, Morgan, Michael J., Choksi, Swati, Zhang, Yan, Kim, You-Sun, Liu, Zheng-gang
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926307/
https://www.ncbi.nlm.nih.gov/pubmed/20711193
http://dx.doi.org/10.1038/ni.1918