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MicroRNAs modulate the noncanonical NF-κB pathway by regulating IKKα expression during macrophage differentiation
MicroRNAs are key regulators in many biological processes including cell differentiation. Here we show that during human monocyte-macrophage differentiation, the expression of the microRNAs miR-223, miR-15a, and miR-16 is dramatically decreased, leading to increased expression of the serine-threonin...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926307/ https://www.ncbi.nlm.nih.gov/pubmed/20711193 http://dx.doi.org/10.1038/ni.1918 |